Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

Abstract Background Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models. Methods Safety, tolerability, and plasma pharmacokinetics o...

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Main Authors: Gurudatt Chandorkar (Author), Qiao Zhan (Author), Julie Donovan (Author), Shruta Rege (Author), Hernando Patino (Author)
Format: Book
Published: BMC, 2017-03-01T00:00:00Z.
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3rd Floor Main Library

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