New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors

• Hlavní autoři: Chenkai Cui (Autor), Xuefei Tian (Autor), Linting Wei (Autor), Yinhong Wang (Autor), Kexin Wang (Autor), Rongguo Fu (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Dipeptidyl peptidase 8 (DPP8) and 9 (DPP9) are widely expressed in mammals including humans, mainly locate in the cytoplasm. The DPP8 and DPP9 (DPP8/9) belong to serine proteolytic enzymes, they can recognize and cleave N-terminal dipeptides of specific substrates if proline is at the penultimate po...