Accuracy of next-generation sequencing for molecular profiling of small specimen of lung cancer: a prospective pilot study of side-by-side comparison

• Main Authors: Xiaosong Ben (Author), Dan Tian (Author), Weitao Zhuang (Author), Rixin Chen (Author), Sichao Wang (Author), Zihao Zhou (Author), Cheng Deng (Author), Ruiqing Shi (Author), Songlin Liu (Author), Dongkun Zhang (Author), Jiming Tang (Author), Liang Xie (Author), Haiyu Zhou (Author), Zhou Zhang (Author), Min Li (Author), Xuanye Zhang (Author), Guibin Qiao (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Successful practice of precision medicine in advanced lung cancers relies on therapeutic regimens tailored to individual molecular characteristics. The aim of this study was to investigate the accuracy of small specimens for molecular profiling using next-generation sequencing (N...