Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway

• Main Authors: Fang Xianjun (Author), Xian Xirui (Author), Tang Jie (Author), Mu Huiwen (Author), Zheng Shaojun (Author), Ling Qiaoyun (Author), Liu Yunxin (Author), Sun Xuqun (Author)
• Format: Book
• Published: Elsevier, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Momordin Ic (MI) is a natural pentacyclic triterpenoid enriched in various Chinese natural medicines such as the fruit of Kochia scoparia (L.) Schrad. Studies have shown that MI presents antitumor properties in liver and prostate cancers. However, the activity and potential mechanisms of MI against...