Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in In Vivo Rat Models

Traumatic and degenerative lesions of articular cartilage usually progress to osteoarthritis (OA), a leading cause of disability in humans. MicroRNAs (miRNAs) can regulate the differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs) and play important roles in the expression of g...

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Main Authors: Dawoon Baek (Author), Kyoung-Mi Lee (Author), Ki Won Park (Author), Jae Wan Suh (Author), Seong Mi Choi (Author), Kwang Hwan Park (Author), Jin Woo Lee (Author), Sung-Hwan Kim (Author)
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Publicado em: Elsevier, 2018-12-01T00:00:00Z.
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