Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in In Vivo Rat Models

• Main Authors: Dawoon Baek (Author), Kyoung-Mi Lee (Author), Ki Won Park (Author), Jae Wan Suh (Author), Seong Mi Choi (Author), Kwang Hwan Park (Author), Jin Woo Lee (Author), Sung-Hwan Kim (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Traumatic and degenerative lesions of articular cartilage usually progress to osteoarthritis (OA), a leading cause of disability in humans. MicroRNAs (miRNAs) can regulate the differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs) and play important roles in the expression of g...