CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease

CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease

Abstract The endocannabinoid CB2 receptor system has been implicated in the neuropathology of Alzheimer's disease (AD). In order to investigate the impact of the CB2 receptor system on AD pathology, a colony of mice with a deleted CB2 receptor gene, CNR2, was established on a transgenic human m...

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Main Authors: Jeremy Koppel (Author), Valerie Vingtdeux (Author), Philippe Marambaud (Author), Cristina d'Abramo (Author), Heidy Jimenez (Author), Mark Stauber (Author), Rachel Friedman (Author), Peter Davies (Author)
Format: Book
Published: BMC, 2013-10-01T00:00:00Z.
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3rd Floor Main Library

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