Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells
ATPase family AAA domain-containing protein 2 (ATAD2) has been emerging as a hot anti-cancer drugable target due to its oncogenic epigenetic modification closely associated with cancer cells proliferation, apoptosis, migration and drug resistance. In this study, we design a series of theophylline de...
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Format: | Book |
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Taylor & Francis Group,
2023-12-01T00:00:00Z.
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Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |