Physical exercise shapes the mouse brain epigenome

• Main Authors: Rocío G. Urdinguio (Author), Juan Ramon Tejedor (Author), Manuel Fernández-Sanjurjo (Author), Raúl F. Pérez (Author), Alfonso Peñarroya (Author), Cecilia Ferrero (Author), Helena Codina-Martínez (Author), Carlos Díez-Planelles (Author), Paola Pinto-Hernández (Author), Juan Castilla-Silgado (Author), Almudena Coto-Vilcapoma (Author), Sergio Díez-Robles (Author), Noelia Blanco-Agudín (Author), Cristina Tomás-Zapico (Author), Eduardo Iglesias-Gutiérrez (Author), Benjamín Fernández-García (Author), Agustin F. Fernandez (Author), Mario F. Fraga (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To analyze the genome-wide epigenomic and transcriptomic changes induced by long term resistance or endurance training in the hippocampus of wild-type mice. Methods: We performed whole-genome bisulfite sequencing (WGBS) and RNA sequencing (RNA-seq) of mice hippocampus after 4 weeks of spe...