Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors

Considering the unrecognised physio-pathological role of human carbonic anhydrase III (hCA III), a structure-based drug design was set up to identify the first-in-class potent and selective inhibitors of this neglected isoform. hCA III targeting was planned considering a unique feature of its active...

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Autores principales: Simone Giovannuzzi (Autor), Alessandro Bonardi (Autor), Paola Gratteri (Autor), Alessio Nocentini (Autor), Claudiu T. Supuran (Autor)
Formato: Libro
Publicado: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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