Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression

Purpose: Morbidity associated with and mortality from acute kidney injury (AKI) is gradually increasing, and no efficient drug is available. We explored whether neferine, a bisbenzylisoquinoline alkaloid, attenuated AKI, and the possible mechanisms in play in vivo and in vitro.Methods: We induced AK...

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Main Authors: Huihui Li (Author), Wenhang Chen (Author), Yusa Chen (Author), Qiaoling Zhou (Author), Ping Xiao (Author), Rong Tang (Author), Jing Xue (Author)
Format: Book
Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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