NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

• Main Authors: Jiangyuan Gao (Author), Ruozhou Tom Liu (Author), Sijia Cao (Author), Jing Z. Cui (Author), Aikun Wang (Author), Eleanor To (Author), Joanne A. Matsubara (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Age-related macular degeneration (AMD) is the leading cause of legal blindness in the elderly in industrialized countries. AMD is a multifactorial disease influenced by both genetic and environmental risk factors. Progression of AMD is characterized by an increase in the number and size of drusen, e...