TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice

• Main Authors: Robert Stöhr (Author), Ben Arpad Kappel (Author), Daniela Carnevale (Author), Michele Cavalera (Author), Maria Mavilio (Author), Ivan Arisi (Author), Valentina Fardella (Author), Giuseppe Cifelli (Author), Viviana Casagrande (Author), Stefano Rizza (Author), Antonino Cattaneo (Author), Alessandro Mauriello (Author), Rossella Menghini (Author), Giuseppe Lembo (Author), Massimo Federici (Author)
• Format: Book
• Published: Elsevier, 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Tissue inhibitor of metalloproteinase 3 (TIMP3) is an extracellular matrix (ECM) bound protein, which has been shown to be downregulated in human subjects and experimental models with cardiometabolic disorders, including type 2 diabetes mellitus, hypertension and atherosclerosis. The aim...