Insulin-loaded polymeric mucoadhesive nanoparticles: development, characterization and cytotoxicity evaluation

• Main Authors: Tiago Henrique Honorato Gatti (Author), Josimar Oliveira Eloy (Author), Leonardo Miziara Barboza Ferreira (Author), Isabel Cristine da Silva (Author), Fernando Rogério Pavan (Author), Maria Palmira Daflon Gremião (Author), Marlus Chorilli (Author)
• Format: Book
• Published: Universidade de São Paulo, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Mucoadhesive nanoparticles are particularly interesting for delivery through nasal or pulmonary routes, as an approach to overcome the mucociliary clearance. Moreover, these nanoparticles are attractive for peptide and protein delivery, particularly for insulin to treat diabetes, as an alte...