Evolution of anti-Trypanosoma cruzi antibody production in patients with chronic Chagas disease: Correlation between antibody titers and development of cardiac disease severity.

• Main Authors: Ingebourg Georg (Author), Alejandro Marcel Hasslocher-Moreno (Author), Sergio Salles Xavier (Author), Marcelo Teixeira de Holanda (Author), Eric Henrique Roma (Author), Maria da Gloria Bonecini-Almeida (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease is one of the most important endemic infections in Latin America affecting around 6-7 million people. About 30-50% of patients develop the cardiac form of the disease, which can lead to severe cardiac dysfunction and death. In this scenario, the identification of immunological markers...