Poloxamer-enhanced solubility of griseofulvin and its related antifungal activity against Trichophyton spp.

Poloxamer-enhanced solubility of griseofulvin and its related antifungal activity against Trichophyton spp.

Abstract Poorly water-soluble drugs, such as the antifungal drug griseofulvin (GF), exhibit limited bioavailability, despite their high membrane permeability. Several technological approaches have been proposed to enhance the water solubility and bioavailability of GF, including micellar solubilizat...

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Main Authors: Vanessa Pittol (Author), Kleyton Santos Veras (Author), Samuel Kaiser (Author), Letícia Jacobi Danielli (Author), Alexandre Meneghello Fuentefria (Author), George González Ortega (Author)
Format: Book
Published: Universidade de São Paulo, 2022-08-01T00:00:00Z.
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