The cholesterol-lowering effect of statins is modified by LILRB5 intolerance genotype: Results from a recruit-by-genotype clinical trial

• 主要な著者: Aleksi Tornio (著者), Margherita Bigossi (著者), Moneeza K. Siddiqui (著者), Gwen Kennedy (著者), Ala'a Melhem (著者), Mehul K. Chourasia (著者), Cyrielle Maroteau (著者), Roberto Pola (著者), Daniel I. Chasman (著者), Alexander S. F. Doney (著者), Colin N. A. Palmer (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background/Aims: Statin intolerance leads to poor adherence to statin therapy, resulting in a failure to achieve desired cholesterol reduction and adverse outcomes. The LILRB5 Asp247Gly genotype has been identified as being associated with statin intolerance and statin-induced myalgia. We conducted...