The cholesterol-lowering effect of statins is modified by LILRB5 intolerance genotype: Results from a recruit-by-genotype clinical trial

• Main Authors: Aleksi Tornio (Author), Margherita Bigossi (Author), Moneeza K. Siddiqui (Author), Gwen Kennedy (Author), Ala'a Melhem (Author), Mehul K. Chourasia (Author), Cyrielle Maroteau (Author), Roberto Pola (Author), Daniel I. Chasman (Author), Alexander S. F. Doney (Author), Colin N. A. Palmer (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Statin intolerance leads to poor adherence to statin therapy, resulting in a failure to achieve desired cholesterol reduction and adverse outcomes. The LILRB5 Asp247Gly genotype has been identified as being associated with statin intolerance and statin-induced myalgia. We conducted...