Prevention of Wogonin on Colorectal Cancer Tumorigenesis by Regulating p53 Nuclear Translocation

• Main Authors: Qian Feng (Author), Haojia Wang (Author), Jiaying Pang (Author), Liyan Ji (Author), Jiada Han (Author), Ying Wang (Author), Xiaoxiao Qi (Author), Zhongqiu Liu (Author), Linlin Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The tumor suppressor protein p53 plays an important role in the development and progression of colon cancer, and the subcellular organelle localization directly affects its function. Wogonin (5,7-dihydroxy-8-methoxyflavone), a mono-flavonoid extracted from root of Scutellaria baicalensis Georgi, pos...