Novel Findings for the Development of Drug Therapy for Various Liver Diseases: Liver Microsomal Triglyceride Transfer Protein Activator May Be a Possible Therapeutic Agent in Non-alcoholic Steatohepatitis

• Main Authors: Koji Fujita (Author), Kento Imajo (Author), Yoshiyasu Shinohara (Author), Yuichi Nozaki (Author), Koichiro Wada (Author), Masato Yoneda (Author), Hiroki Endo (Author), Hirokazu Takahashi (Author), Yasunobu Abe (Author), Masahiko Inamori (Author), Takeshi Shimamura (Author), Noritoshi Kobayashi (Author), Hiroyuki Kirikoshi (Author), Kensuke Kubota (Author), Satoru Saito (Author), Atsushi Nakajima (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The factors involved in the progression of non-alcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH) are not fully understood and thus it is urgently needed to elucidate these factors. Steatosis is not causal in the development of NASH, but rather it sensitizes the liver to the damagin...