CC-223, NSC781406, and BGT226 Exerts a Cytotoxic Effect Against Pancreatic Cancer Cells via mTOR Signaling

• Main Authors: Yangyang Guo (Author), Hengyue Zhu (Author), Min Weng (Author), Hewei Zhang (Author), Cheng Wang (Author), Linxiao Sun (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The mTOR signaling pathway is abnormally activated in pancreatic cancer and is related to tumor glucose metabolism. However, its specific regulation mechanism is still unclear. Therefore, this study aims to investigate whether Sestrin2 affects the glucose metabolism of pancreatic cancer by modulatin...