Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458) in patients with acute lymphoblastic leukemia

Abstract JZP458 is a recombinant Erwinia chrysanthemi asparaginase for patients with acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LBL) who have developed hypersensitivity to Escherichia coli-derived asparaginases. A population pharmacokinetic (PopPK) model was developed for intramuscul...

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Main Authors: Tong Lin (Author), Tajhia Whigham (Author), Indrasiri Fernando (Author), Mi Rim Choi (Author), Qi Wang (Author), Jeffrey A. Silverman (Author)
Format: Book
Published: Wiley, 2023-05-01T00:00:00Z.
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