HJ11 decoction restrains development of myocardial ischemia-reperfusion injury in rats by suppressing ACSL4-mediated ferroptosis

• Main Authors: Fangyuan Zhang (Author), Ziyun Li (Author), Ping Gao (Author), Jiaxi Zou (Author), Yuting Cui (Author), Yi Qian (Author), Renjun Gu (Author), Weiming Xu (Author), Jingqing Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HJ11 is a novel traditional Chinese medicine developed from the appropriate addition and reduction of Si-Miao-Yong-An decoction, which has been commonly used to treat ischemia-reperfusion (I/R) injury in the clinical setting. However, the mechanism of action of HJ11 components remains unclear. Ferro...