Design, synthesis, and molecular docking of cysteine-based sulphonamide derivatives as antimicrobial agents

• Main Authors: Melford C Egbujor (Author), Uchechukwu C Okoro (Author), Sunday N Okafor (Author), Samuel A Egu (Author), Ifeanyi S Amasiatu (Author), Pius I Egwuatu (Author), Odera R Umeh (Author), Eziafakaego M Ibo (Author)
• Format: Bog
• Udgivet: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Background and purpose: The preponderance of microbial infections remains a global challenge. In the present study, synthesis of novel cysteine-based antimicrobial agents and their biological evaluation is reported. Experimental approach: The reaction of p-toluenesulphonyl chloride with cysteine aff...