Establishment of an oral squamous cell carcinoma cell line expressing vascular endothelial growth factor a and its two receptors

• Main Authors: Hanako Araki-Maeda (Author), Mutsuki Kawabe (Author), Yuji Omori (Author), Koji Yamanegi (Author), Kazunari Yoshida (Author), Kyohei Yoshikawa (Author), Kazuki Takaoka (Author), Kazuma Noguchi (Author), Yoshiro Nakano (Author), Hiromitsu Kishimoto (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Vascular endothelial growth factor receptor (VEGFR) expression in oral squamous cell carcinoma (OSCC) promotes tumor growth through both autocrine and paracrine signaling. VEGF-positive OSCC cases are associated with a high depth of invasion, increased metastasis, and poor progno...