Case report: response to immunotherapy and association with the fh gene in hereditary leiomyomatosis and renal cell cancer-associated renal cell cancer

• Главные авторы: Fangfang Gao (Автор), Dejian Gu (Автор), He Zhang (Автор), Chao Shi (Автор), Feng Du (Автор), Bo Zheng (Автор), Huijuan Wu (Автор), Yanqiu Zhao (Автор)
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• Опубликовано: BMC, 2024-08-01T00:00:00Z.
• Предметы: article
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Abstract Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare autosomal dominant syndrome caused by a germline mutation in the fumarate hydratase (FH) gene that manifests with cutaneous leiomyomas, uterine fibroids, and renal cell cancer (RCC). Patients with HLRCC-associated RCC (HLRCC-...