Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection.

• Main Authors: Anitra L Farrow (Author), Girish Rachakonda (Author), Linlin Gu (Author), Valentina Krendelchtchikova (Author), Pius N Nde (Author), Siddharth Pratap (Author), Maria F Lima (Author), Fernando Villalta (Author), Qiana L Matthews (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi is the causative agent of Chagas disease. Chagas disease is an endemic infection that affects over 8 million people throughout Latin America and now has become a global challenge. The current pharmacological treatment of patients is unsuccessful in most cases, highly toxic, and no...