Preparation of Nanoparticles Loaded with Membrane-Impermeable Peptide AC3-I and Its Protective Effect on Myocardial Ischemia and Reperfusion

• Autores principales: Yi Liu (Autor), Yingyi Niu (Autor), Wenjie Zhang (Autor), Kaikai Wang (Autor), Tianqing Liu (Autor), Weizhong Zhu (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2024-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Purpose: It is well known that inhibition of Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) provides cardiac protection in cases of myocardial ischemia-reperfusion injury. However, there are currently no cytoplasm-impermeable drugs that target CaMKII. The aim of this stu...