Comparative gene expression analysis throughout the life cycle of Leishmania braziliensis: diversity of expression profiles among clinical isolates.

• Main Authors: Vanessa Adaui (Author), Denis Castillo (Author), Mirko Zimic (Author), Andres Gutierrez (Author), Saskia Decuypere (Author), Manu Vanaerschot (Author), Simonne De Doncker (Author), Kathy Schnorbusch (Author), Ilse Maes (Author), Gert Van der Auwera (Author), Louis Maes (Author), Alejandro Llanos-Cuentas (Author), Jorge Arevalo (Author), Jean-Claude Dujardin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Most of the Leishmania genome is reported to be constitutively expressed during the life cycle of the parasite, with a few regulated genes. Inter-species comparative transcriptomics evidenced a low number of species-specific differences related to differentially distributed genes or the...