The Pharmacological and Structural Basis of the AahII-NaV1.5 Interaction and Modulation by the Anti-AahII Nb10 Nanobody
Scorpion α-toxins are neurotoxins that target the fast inactivation mechanism of voltage-gated sodium (NaV) channels leading to several neuro- and cardiotoxic effects in mammals. The toxin AahII is the most active α-toxin from the North African scorpion Androctonus australis Hector that slows the fa...
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Main Authors: | Riadh Hmaidi (Author), Ayoub Ksouri (Author), Rahma Benabderrazek (Author), Viviane Antonietti (Author), Pascal Sonnet (Author), Mathieu Gautier (Author), Balkiss Bouhaouala-Zahar (Author), Halima Ouadid-Ahidouch (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2022-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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