Pirin, an Nrf2-Regulated Protein, Is Overexpressed in Human Colorectal Tumors

• Main Authors: Ying Zhang (Author), Elena V. Knatko (Author), Maureen Higgins (Author), Sharadha Dayalan Naidu (Author), Gillian Smith (Author), Tadashi Honda (Author), Laureano de la Vega (Author), Albena T. Dinkova-Kostova (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The evolutionary conserved non-heme Fe-containing protein pirin has been implicated as an important factor in cell proliferation, migration, invasion, and tumour progression of melanoma, breast, lung, cervical, prostate, and oral cancers. Here we found that pirin is overexpressed in human colorectal...