Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.

• Hoofdauteurs: Mark W Robinson (Auteur), Ileana Corvo (Auteur), Peter M Jones (Auteur), Anthony M George (Auteur), Matthew P Padula (Auteur), Joyce To (Auteur), Martin Cancela (Auteur), Gabriel Rinaldi (Auteur), Jose F Tort (Auteur), Leda Roche (Auteur), John P Dalton (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

BACKGROUND: The temporal expression and secretion of distinct members of a family of virulence-associated cathepsin L cysteine peptidases (FhCL) correlates with the entry and migration of the helminth pathogen Fasciola hepatica in the host. Thus, infective larvae traversing the gut wall secrete cath...