Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency

• Main Authors: Peter J. McGuire (Author), Tatiana N. Tarasenko (Author), Tony Wang (Author), Ezra Levy (Author), Patricia M. Zerfas (Author), Thomas Moran (Author), Hye Seung Lee (Author), Brian J. Bequette (Author), George A. Diaz (Author)
• Format: Book
• Published: The Company of Biologists, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The urea cycle functions to incorporate ammonia, generated by normal metabolism, into urea. Urea cycle disorders (UCDs) are caused by loss of function in any of the enzymes responsible for ureagenesis, and are characterized by life-threatening episodes of acute metabolic decompensation with hyperamm...