Exploring the safety and efficacy of phytomedicine Petiveria alliacea extract (Esperanza) in patients with metastatic gastrointestinal tumors and acute leukemias: study protocol for a phase Ib/randomized double blind phase II trial (PA001)

• Main Authors: Ricardo Ballesteros-Ramírez (Author), Paola Pinilla (Author), Jesús Sanchéz (Author), Mónica Arévalo (Author), Elio Sanchez (Author), Pablo Aschner (Author), Claudia Urueña (Author), Susana Fiorentino (Author)
• פורמט: ספר
• יצא לאור: BMC, 2023-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background The energy metabolism of drug-resistant tumor cells can provide a survival advantage during therapy, and treatment itself may influence metabolic reprogramming. Petiveria alliacea (Traditional name: Anamu) could inhibit glycolysis and OXPHOX modulating tumor metabolism, making it...