Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations

• Main Authors: Ruqaiyyah Siddiqui (Author), Mutasem Rawas-Qalaji (Author), Mohammed I. El-Gamal (Author), Sreedevi Sajeev (Author), Jayalakshmi Jagal (Author), Seyed-Omar Zaraei (Author), Rawan M. Sbenati (Author), Hanan S. Anbar (Author), Wolfgang Dohle (Author), Barry V. L. Potter (Author), Naveed Ahmed Khan (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pathogenic <i>Acanthamoeba</i> produce keratitis and fatal granulomatous amoebic encephalitis. Treatment remains problematic and often ineffective, suggesting the need for the discovery of novel compounds. For the first time, here we evaluated the effects of the anticancer drugs Irosusta...