Holistic acceptability of an adult levofloxacin formulation in children and adolescents on a tuberculosis preventive treatment trial.

• Main Authors: Susan E Purchase (Author), Dillon T Wademan (Author), Nosibusiso L Tshetu (Author), Mohhadiah Rafique (Author), Graeme Hoddinott (Author), James A Seddon (Author), H Simon Schaaf (Author), Anneke C Hesseling (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-resistant tuberculosis (TB) is threatening global TB control. Although formulations designed for children are a priority, adult levofloxacin formulations are widely used in TB treatment and prevention. TB-CHAMP was a cluster-randomised, placebo-controlled trial evaluating the efficacy and safet...