Comparison of dengue virus type 2-specific small RNAs from RNA interference-competent and -incompetent mosquito cells.

• Principais autores: Jaclyn C Scott (Autor), Doug E Brackney (Autor), Corey L Campbell (Autor), Virginie Bondu-Hawkins (Autor), Brian Hjelle (Autor), Greg D Ebel (Autor), Ken E Olson (Autor), Carol D Blair (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2010-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The exogenous RNA interference (RNAi) pathway is an important antiviral defense against arboviruses in mosquitoes, and virus-specific small interfering (si)RNAs are key components of this pathway. Understanding the biogenesis of siRNAs in mosquitoes could have important ramifications in using RNAi t...