Comparison of dengue virus type 2-specific small RNAs from RNA interference-competent and -incompetent mosquito cells.

• Main Authors: Jaclyn C Scott (Author), Doug E Brackney (Author), Corey L Campbell (Author), Virginie Bondu-Hawkins (Author), Brian Hjelle (Author), Greg D Ebel (Author), Ken E Olson (Author), Carol D Blair (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The exogenous RNA interference (RNAi) pathway is an important antiviral defense against arboviruses in mosquitoes, and virus-specific small interfering (si)RNAs are key components of this pathway. Understanding the biogenesis of siRNAs in mosquitoes could have important ramifications in using RNAi t...