Diagnosis of GATA2 haplo-insufficiency in a young woman prompted by pancytopenia with deficiencies of B-cell and dendritic cell development

• Asıl Yazarlar: Allen Sanyi (Yazar), David L. Jaye (Yazar), Cecilia B. Rosand (Yazar), Amanda Box (Yazar), Chandrakasan Shanmuganathan (Yazar), Edmund K. Waller (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2018-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background GATA2 deficiency presents with a spectrum of phenotypes including increased susceptibility to viral and bacterial infections, multi-lineage cytopenias, aplastic anemia, leukemic transformation and lymphedema. Allogeneic transplantation is only curative therapy for GATA2 deficienc...