Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

SARS-CoV-2 Spike protein was predicted by molecular docking to bind the host cell surface GRP78, which was suggested as a putative good molecular target to inhibit Covid-19. We aimed to confirm that GRP78 gene expression was increased in blood of SARS-CoV-2 (+) versus SARS-CoV-2 (−) pneumonia patien...

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Main Authors: Andreia Palmeira (Author), Emília Sousa (Author), Aylin Köseler (Author), Ramazan Sabirli (Author), Tarık Gören (Author), İbrahim Türkçüer (Author), Özgür Kurt (Author), Madalena M. Pinto (Author), M. Helena Vasconcelos (Author)
Format: Book
Published: MDPI AG, 2020-06-01T00:00:00Z.
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3rd Floor Main Library

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