The Antipsychotic and Antiemetic Drug Prochlorperazine Delays the Ventricular Repolarization of the In Situ Canine Heart

• Hoofdauteurs: Yoshioki Satoh (Auteur), Atsushi Sugiyama (Auteur), Akira Takahara (Auteur), Kentaro Ando (Auteur), Kai Wang (Auteur), Sachiko Honsho (Auteur), Keitaro Hashimoto (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2005-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Electropharmacological effect of the antipsychotic and antiemetic drug prochlorperazine was assessed using the halothane-anesthetized in vivo canine model (n = 5). Up to 10 times higher than the clinically relevant doses of prochlorperazine (≤ 3mg/kg, i.v.) did not induce cardiohemodynamic collapse...