To Be Drug or Prodrug: Structure-Property Exploratory Approach Regarding Oral Bioavailability
Purpose. Prodrug design is a strategy that can be used to adjust physicochemical properties of drugs in order to overcome pharmacokinetic problems, such as poor oral bioavailability. However, Lipinski´s and Veber´s rules predict whether compounds will have absorption problems even before the design...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2014-11-01T00:00:00Z.
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Internet
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |