Effect of Glycerol on Fosfomycin Activity against <i>Escherichia coli</i>

• Main Authors: Miriam Ortiz-Padilla (Author), Inés Portillo-Calderón (Author), Ana Velázquez-Escudero (Author), Jesús Rodríguez-Baño (Author), Álvaro Pascual (Author), José Manuel Rodríguez-Martínez (Author), Fernando Docobo-Pérez (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fosfomycin is an antimicrobial that inhibits the biosynthesis of peptidoglycan by entering the bacteria through two channels (UhpT and GlpT). Glycerol is clinically used as a treatment for elevated intracranial pressure and induces the expression of <i>glpT</i> in <i>Escherichia co...