Role of COX-2/mPGES-1/Prostaglandin E2 Cascade in Kidney Injury

• Main Authors: Zhanjun Jia (Author), Yue Zhang (Author), Guixia Ding (Author), Kristina Marie Heiney (Author), Songming Huang (Author), Aihua Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

COX-2/mPGES-1/PGE2 cascade plays critical roles in modulating many physiological and pathological actions in different organs. In the kidney, this cascade is of high importance in regulating fluid metabolism, blood pressure, and renal hemodynamics. Under some disease conditions, this cascade display...