Suppression of NLRP3 Inflammasome by Erythropoietin via the EPOR/JAK2/STAT3 Pathway Contributes to Attenuation of Acute Lung Injury in Mice

• Main Authors: Fei Cao (Author), Xinyi Tian (Author), Zhongwang Li (Author), Ya Lv (Author), Jun Han (Author), Rong Zhuang (Author), Bihuan Cheng (Author), Yuqiang Gong (Author), Binyu Ying (Author), Shengwei Jin (Author), Ye Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and devastating clinical disorders with high mortality and no specific therapy. An excessive inflammatory response results in the progression of ALI/ARDS, and the NLRP3 inflammasome is a key participant in inflammation...