Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses

• Main Authors: Fanping Wang (Author), Yanhua Li (Author), Can Yang (Author), Yonghui Mu (Author), Yan Wang (Author), Wei Zhang (Author), Yonghui Yang (Author), Chen Chen (Author), Shijun Song (Author), Zhifa Shen (Author), Wenjun Wang (Author), Junpeng Li (Author), Jingjing Zhai (Author), Kang Guo (Author), Ruili Sun (Author), Lili Yu (Author), Mingyong Wang (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2019-01-01T00:00:00Z.
• Fag: article
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Peptidoglycan (PGN), as the major components of the bacterial cell wall, is known to cause excessive proinflammatory cytokine production. Toll-like receptor 2 (TLR2) is abundantly expressed on immune cells and has been shown to be involved in PGN-induced signaling. Although more and more evidences h...