An integrated strategy for comprehensive characterization of metabolites and metabolic profiles of bufadienolides from Venenum Bufonis in rats

• Main Authors: Wen-Long Wei (Author), Hao-Jv Li (Author), Wen-Zhi Yang (Author), Hua Qu (Author), Zhen-Wei Li (Author), Chang-Liang Yao (Author), Jin-Jun Hou (Author), Wan-Ying Wu (Author), De-An Guo (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Comprehensive characterization of metabolites and metabolic profiles in plasma has considerable significance in determining the efficacy and safety of traditional Chinese medicine (TCM) in vivo. However, this process is usually hindered by the insufficient characteristic fragments of metabolites, ub...