Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

• Main Authors: Sang-Hwan Ji (Author), Ki Young Huh (Author), Jaeseong Oh (Author), Hee-Jeong Jeong (Author), Young-Eun Jang (Author), Eun-Hee Kim (Author), Ji-Hyun Lee (Author), Jin-Tae Kim (Author), Hee-Soo Kim (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg. We investigated the pharmacokinetics and pharmacodynamics of sugammadex in Korean children.Methods: Chil...