Drug Nanocrystals: Focus on Brain Delivery from Therapeutic to Diagnostic Applications

• Egile Nagusiak: Elide Zingale (Egilea), Angela Bonaccorso (Egilea), Claudia Carbone (Egilea), Teresa Musumeci (Egilea), Rosario Pignatello (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The development of new drugs is often hindered by low solubility in water, a problem common to nearly 90% of natural and/or synthetic molecules in the discovery pipeline. Nanocrystalline drug technology involves the reduction in the bulk particle size down to the nanosize range, thus modifying its p...