Fucoidan-functionalized activated platelet-hitchhiking micelles simultaneously track tumor cells and remodel the immunosuppressive microenvironment for efficient metastatic cancer treatment

• Main Authors: Rong Guo (Author), Miao Deng (Author), Xuan He (Author), Mengmeng Li (Author), Jiaxin Li (Author), Penghui He (Author), Houqin Liu (Author), Man Li (Author), Zhirong Zhang (Author), Qin He (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor metastasis is responsible for most mortality in cancer patients, and remains a challenge in clinical cancer treatment. Platelets can be recruited and activated by tumor cells, then adhere to circulating tumor cells (CTCs) and assist tumor cells extravasate in distant organs. Therefore, nanopar...