Modulation of Methotrexate Release from Nano-Hydrogels via Drug-Transition Metal Complexation

• मुख्य लेखकों: Mahsa Taheri (लेखक), Samirasadat Abolmaali (लेखक), Mozhgan Abedanzadeh (लेखक), Samaneh Mohammadi (लेखक), Sanaz Javanmardi (लेखक), Alimohammad Tamaddon (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Shiraz University of Medical Sciences, 2020-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Despite the extensive application of methotrexate (MTX) as a chemotherapeutic agent and an immune system suppressor, its therapeutic implementation has been limited due to its poor pharmacokinetics, saturable cellular transport, and insufficient response in some conditions. These limitations have re...