Modeling the dynamics of Plasmodium vivax infection and hypnozoite reactivation in vivo.

• Main Authors: Adeshina I Adekunle (Author), Mykola Pinkevych (Author), Rose McGready (Author), Christine Luxemburger (Author), Lisa J White (Author), François Nosten (Author), Deborah Cromer (Author), Miles P Davenport (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dynamics of Plasmodium vivax infection is characterized by reactivation of hypnozoites at varying time intervals. The relative contribution of new P. vivax infection and reactivation of dormant liver stage hypnozoites to initiation of blood stage infection is unclear. In this study, we investiga...