A New Method for Ethical and Efficient Evidence Generation for Off-Label Medication Use in Oncology (A Case Study in Glioblastoma)

• Main Authors: Samir Agrawal (Author), Padman Vamadevan (Author), Ndaba Mazibuko (Author), Robin Bannister (Author), Raphael Swery (Author), Shanna Wilson (Author), Sarah Edwards (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In oncology, preclinical and early clinical data increasingly support the use of a number of candidate "non-cancer" drugs in an off-label setting against multiple tumor types. In particular, metabolically targeted drugs show promise as adjuvant chemo and radiosensitizers, improving or rest...